Fondé en 2005 en Principauté de Monaco, le laboratoire Sérélys Pharma® est pionnier dans les solutions non-hormonales pour les femmes en période de périménopause et ménopause. Leader des compléments alimentaires à base d’extraits cytoplasmiques purifiés de pollens, il a mis au point des complexes PureCyTonin®.

La marque Sérélys® a pour vocation le bien-être de la femme. Sérélys® aide les femmes à assumer leur féminité et à s’épanouir à tout âge.

Références bibliographiques

PERI / MENOPAUSE :

# Les matières premières pollen utilisées pour la fabrication des Extraits Cytoplasmiques Purifiés de Pollens de Sérélys sont des produits naturels de plantes

  1. Freeman EW and Sherif K. Prevalence of hot flushes and night sweats around the world : asystematic review. Climacteric. 2007 Vol 10(3) :197-214.
  2. MOSCONI et al.,   Neurology  2017, 89, 1382-1390 Le risque de la maladie d’Alzheimer (MA) varie selon le sexe: influence de la transition ménopausique
  3. Winther K, Rein E and Hedman C. Sérélys®, a herbal remedy made from pollen extracts, reduces hot flushes and improves quality of life in menopausal women: a randomized, placebo-controlled, parallel study. Climateric 2005. 8:162–170.
  4. Hellstrom AC and Muntzing J The pollen extract Sérélys – a non estrogenic alternative to hormonetherapy in women with menopausal symptoms. Menopause 2012. Vol. 19(7) 825-829.
  5. Elia D and Mares P. Evaluation de la tolérance et de l’efficacité d’un complément alimentaire Sérélys® chez les femmes en période de ménopause. Génésis 2008. 135: 12-15.
  6. Recommandations T.H.M ANSES – Juillet 2004  https://www.efsa.europa.eu/en/efsajournal/pub/4246
  7. The Lancet journal published online August 29, 2019 Collaborative Group on Hormonal Factors in Breast Cancer. “Type and timing of menopausal hormone therapy and breast cancer risk: individual participant meta-analysis of the worldwide epidemiological evidence”
  8. Seeger H, Ruan X, Neubauer H, Brucker S, Mueck A. Membrane-initiated effects of Serelys® on proliferation and apoptosis of human breast cancer cells Gynecological Endocrinology 2017.

LE CAPITAL OSSEUX :

  1. Sowers M, Crutchfield M, Bandekar R, Randolph JF, Shapiro B, Schork MA, Jannausch M. Bone minera1 density and its change in pre and perimenopausal white women: the Michigan Bone Health Study. J Bone Miner Res., 1998;
  2. Riggs BL, Melton LJ 3rd. Involutional osteoporosis. The New England Journal of Medecine, 1986; 3 14 (26): 1676-86.
  3. Knapen M.H.J. et al., Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women. Osteoporosis International, 2013. Volume 24(9), 2499-507.
  4. Knapen MHJ et al. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women: double-blind randomized clinical trial. Thrombosis and Haemostasis, 2015. Volume 113(5), 1135-44.
  5. Winther K, Rein E and Hedman C. Sérélys®, a herbal remedy made from pollen extracts, reduces hot flushes and improves quality of life in menopausal women: a randomized, placebo-controlled, parallel study. Climateric 2005. 8:162–170.
  6. Hellstrom AC and Muntzing J The pollen extract Serelys – a nonestrogenic alternative to hormonetherapy in women with menopausal symptoms. Menopause 2012. Vol. 19(7) 825-829.

MÉNOPAUSE ARTIFICIELLE :

  1. https://www.efsa.europa.eu/en/efsajournal/pub/4246
  2. Nicoletta Biglia N, Bounous V, De Seta F, Lello S, Nappi R  and Paoletti AM. Non-hormonal strategies for managing menopausal symptoms in cancer survivors: an update ecancer 2019. 13:909; www.ecancer.org
  3. Espié M. Bouffées de chaleur et cancer du sein : Quelle prise en charge efficace et sans risque ? Cancer au féminin, 2013. 1-16
  4. Seeger H, Ruan X, Neubauer H, Brucker S, Mueck A. Membrane-initiated effects of Serelys® on proliferation and apoptosis of human breast cancer cells Gynecological Endocrinology 2017.
  5.  Goldstein S, Espie M and Druckmann R: Does purified Swedish pollen extract, a nonhormonal treatment for vasomotor symptoms, inhibit the CYP2D6 enzyme system? Menopause: The Journal of The North American Menopause Society 2015. 22(11):  1212-1214

PureCyTonin®

# Les Extraits Cytoplasmiques Purifiés de Pollens sont d’origine naturelle.

  1. Winther K, Rein E and Hedman C. Serelys®, a herbal remedy made from pollen extracts, reduces hot flushes and improves quality of life in menopausal women: a randomized, placebo-controlled, parallel study. Climateric 2005. 8:162–170.
  2. Hellstrom AC and Muntzing J The pollen extract Serelys – a non estrogenic alternative to hormonetherapy in women with menopausal symptoms. Menopause 2012. Vol. 19(7) 825-829.
  3. Elia D and Mares P. Evaluation de la tolérance et de l’efficacité d’un complément alimentaire Sérélys® chez les femmes en période de ménopause. Genesis 2008. 135: 12-15.
  4. Druckmann R, Lachowsky M and Elia D. Evaluation de la qualité de vie, de l’efficacité et de la tolérance de Sérélys chez les femmes en période de péri-ménopause et ménopause. Genesis 2015. 183 : 10-13.
  5. D’Alterio, Giancane E, Cornacchia S, Corda V, Abis P, Zedda P, Orru M, Marotto MF, Pilloni M, Lello S, Capozzi A, Paoletti AM and Melis GB. GCFem, PI82, vitamin E in menopause treatment: benefits for peri and postmenopausal neurovegetative symptoms Multidisciplinary Journal of Women’s Health 2015. 4(1).
  6. Munoz E. Effect of a PE-F/A on estrogenic activity. Internal report Sérélys Pharma, 2012.
  7. Seeger H, Ruan X, Neubauer H, Brucker S, Mueck A. Membrane-initiated effects of Serelys® on proliferation and apoptosis of human breast cancer cells Gynecological Endocrinology 2017.
  8. Gerhardsen G, Hansen AV, Killi M, Fornitz GG, Pedersen F, Roos SB. The efficacy of Serelys® in women with premenstrual syndrome: a randomised, double-blind, parallel-group, placebo-controlled, multicentre study. Advances in Therapy 2008. 25 (6): 595-607.
  9. Winther K and Hedman C. Assessment of the effects of the herbal remedy Serelys on the symptoms of premenstrual syndrome a randomized, double blind, placebo-controlled study. Current Therapeutic Research 2002. 63 (5): 344-353.
  10. Winther K et al., A double blinded, randomized, placebo controlled, parallel study of pollen pistil extract (Serelys) on women reporting irritability as predominant PMS symptoms. Journal of Herbal Medicine 2018. 12 : 23-32